Spatial Epidemiology Lab

Université Libre de Bruxelles

At the Spatial Epidemiology Lab (SpELL), we study the effect of spatial factors on the emergence, spread, persistence and evolution of diseases and invasive species. The understanding of key spatial factors, such as climatic, ecological or anthropogenic variables, and their integration into spatial and/or molecular approaches is used to predict the geographical distribution of risk and the environmental factors impacting the dispersal history and dynamic of pathogen spreads, which can contribute to better targetted prevention, surveillance and control measures. We also work toward the development, improvement and application of methods in spatial modelling of biological invasions, ecological niche modelling for risk mapping, and landscape phylogeography. The SpELL is also involved in the assembly of large-scale data sets on farm animals and in studies dedicated to the conservation of insect pollinators.

Recent news

Award from the Centre d'Etude Joséphine-Charlotte for scientific research against viral infections

On October 03 2025 by Simon Dellicour & Marius Gilbert

On October 2, we — Simon Dellicour and Marius Gilbert — received the 2025 prize awarded by the Centre d’Etude Princesse Joséphine-Charlotte for scientific research against viral infections. This is a huge honour to receive this award and recognition for our research work integrating spatial and molecular epidemiology. This is also an opportunity for us to thank the FNRS for their support, the entire Spatial Epidemiology Lab as well as our colleagues and collaborators on these different research projects. Read more...

Fourth edition of the Health Geography and Spatial Epidemiology workshop, organised this year at the ULB

On October 01 2025 by Kyla Serres & Simon Dellicour

On September 29 and 30, the SpELL organised at the ULB the fourth edition of the Health Geography and Spatial Epidemiology workshop, a now yearly meeting coordinated by the homonymous FNRS contact group to federate the Belgian community of researchers and analysts working in these fields. These workshops are a great opportunity for doctoral and post-doctoral researchers to present their work in a supportive environment, as well as to stay informed about each other’s research, encourage collaborations, and plan joint projects. Read more...

New study in PNAS on the comparative performance of novel viral landscape phylogeography approaches

On June 25 2025 by Simon Dellicour

The rapid evolution of RNA viruses implies that their evolutionary and ecological processes occur on the same time scale. Genome sequences of these pathogens therefore can contain information about the processes that govern their transmission and dispersal. Landscape phylogeographic approaches use phylogeographic reconstructions to investigate the impact of environmental factors and variables on the spatial spread of viruses. In this new study, we extend and improve existing approaches and develop three novel landscape phylogeographic methods that can test the impact of continuous environmental factors on the diffusion velocity of viral lineages. Read more...


See all news

Main research topics

Landscape phylogeography

Spatially-explicit phylogeographic analyses can be used to reconstruct the dispersal history of viral lineages. Over the last years, we started exploiting such phylogeographic reconstructions to investigate the impact on environmental factors on the dispersal dynamic of viral lineages (such as their diffusion velocity, dispersal position, and dispersal frequency). Furthermore, we also aim to use phylogeographic reconstruction to assess hypothetical intervention strategies in the context of viral epidemics.

See more

Diseases risk mapping

We further develop and applies methodologies to conduct ecological niche modelling for the risk mapping of infectious diseases. Our research initially focused on avian influenza, with a particular emphasis on the role of agro-ecological factors on its emergence and persistence, but we have then also worked on other important livestock diseases such as bluetongue, bovine tuberculosis, and Nipah virus infections. More recently, we have conducted studies dedicated to the impact of climate and land-use changes on the distribution of pathogens of OneHealth importance such as the Lassa virus in Africa and the West Nile virus in Europe.

See more

Modelling biological invasions

Invading organisms spreading though an heterogeneous landscape are difficult to study using conventional statistical models. We aim to review existing methods, to develop new methodologies to study those type of data, and to compare all methods in their capacity to detect the influence of landscape heterogeneity on the pattern of spread. In particular, we have developed an analytical framework that allows testing the impact of continuous environmental layer as well as barriers on a wavefront progression.

See more